Oncotarget published “TERT and its binding protein: overexpression of GABPA/B in high grade gliomas” which reported that all GA-binding proteins progress through the glioma grades and have the highest expression levels in secondary glioblastomas.
In secondary glioblastomas after chemotherapy, GABPB1 and GABPB1-L are expressed on a lower level than without treatment.
Between primary and secondary glioblastomas with and without chemotherapy, TERT is elevated in the former while GABPB1 is increased in the secondary glioblastomas.
GABPA and GABPB1, GABPB1-L and GABPB1-S positively correlate in primary glioblastomas.
This Oncotarget study confirms the upregulation of TERT in primary glioblastomas while all GABP proteins rise with the malignancy of the gliomas.
This Oncotarget study confirms the upregulation of TERT in primary glioblastomas